Inserm Unité 1085-Irset, France.
Nucleic Acids Res. 2012 Jul;40(Web Server issue):W458-65. doi: 10.1093/nar/gks380. Epub 2012 May 8.
We present gene prioritization system (GPSy), a cross-species gene prioritization system that facilitates the arduous but critical task of prioritizing genes for follow-up functional analyses. GPSy's modular design with regard to species, data sets and scoring strategies enables users to formulate queries in a highly flexible manner. Currently, the system encompasses 20 topics related to conserved biological processes including male gamete development discussed in this article. The web server-based tool is freely available at http://gpsy.genouest.org.
我们提出了基因优先级系统 (GPSy),这是一种跨物种的基因优先级系统,可简化后续功能分析中优先级基因这一艰巨但至关重要的任务。GPSy 在物种、数据集和评分策略方面的模块化设计使用户能够以非常灵活的方式进行查询。目前,该系统包含 20 个与保守生物过程相关的主题,包括本文讨论的雄性配子体发育。基于网络服务器的工具可免费在 http://gpsy.genouest.org 获取。