Russian Academy of Sciences, St. Petersburg Institute for Informatics and Automation, Saint Petersburg, Russia.
J Mol Neurosci. 2012 Sep;48(1):154-60. doi: 10.1007/s12031-012-9793-6. Epub 2012 May 10.
Based on our theory, we have discovered main triplets of amino acid residues in cell-adhesion receptors of marine sponges, which appear also as homologies in several receptor heteromers of human brain. The obtained results strengthen our hypothesis that these triplets may "guide-and-clasp" receptor-receptor interactions.
基于我们的理论,我们在海洋海绵的细胞粘附受体中发现了主要的氨基酸残基三联体,这些三联体在人类大脑的几种受体异源三聚体中也呈现同源性。获得的结果加强了我们的假设,即这些三联体可能“引导和扣合”受体-受体相互作用。