Department of Sport Science, Medical Section, University of Innsbruck, Innsbruck, Austria.
Am J Cardiol. 2012 Aug 15;110(4):594-8. doi: 10.1016/j.amjcard.2012.03.052. Epub 2012 May 10.
Cardiac troponin increases are common in adult marathon finishers. However, data on troponin values for young marathon runners are scarce. Forty young runners (20 healthy male and 20 female) 13 to 17 years old participated in this study. Blood samples were taken before, immediately after, and 24 hours after the race for determination of cardiac troponin T (cTnT) and troponin I (cTnI). Thirty-seven runners completed the race with a mean finishing time of 4 hours 53 minutes. No participant developed an adverse medical event during or after the race. In 30 of 37 participants, levels of cTnT and/or cTnI exceeded upper reference limits of 0.01 and 0.1 ng/ml immediately after the race, and in 3 participants these levels were even higher than the reference range for acute myocardial infarction (>0.1 and >0.5 ng/ml for cTnT and cTnI, respectively). Twenty-four hours after the race no participant had troponin levels exceeding the upper reference limits. Average increases of troponin levels did not differ between sexes. In conclusion, this is the first study to show that cardiac troponin levels increase to a similar extent in male and female adolescent marathon runners as observed in adults. Rapid recovery of troponin levels after a race is indicative of a physiologic rather than a pathologic response.
心肌肌钙蛋白升高在成年马拉松完赛者中很常见。然而，关于年轻马拉松跑者的肌钙蛋白值的数据却很少。本研究纳入了 40 名 13 至 17 岁的年轻跑者（20 名健康男性和 20 名健康女性）。在比赛前、比赛后即刻和 24 小时采集血样，用于测定心肌肌钙蛋白 T（cTnT）和肌钙蛋白 I（cTnI）。37 名跑者完成了比赛，平均完赛时间为 4 小时 53 分钟。没有参与者在比赛期间或之后发生不良医疗事件。在 37 名参与者中的 30 名，cTnT 和/或 cTnI 的水平在比赛后即刻超过了 0.01 和 0.1ng/ml 的上限参考值，在 3 名参与者中，这些水平甚至高于急性心肌梗死的参考范围（cTnT 和 cTnI 分别为>0.1 和>0.5ng/ml）。24 小时后，没有参与者的肌钙蛋白水平超过上限参考值。肌钙蛋白水平的平均升高在性别之间没有差异。总之，这是第一项表明心肌肌钙蛋白水平在男性和女性青少年马拉松跑者中增加程度与成年人相似的研究。比赛后肌钙蛋白水平的快速恢复表明是生理性的而不是病理性的反应。
