SDSU/UCSD Joint Doctoral Program in Clinical Psychology, San Diego, CA 92120, USA.
Vaccine. 2012 Jun 29;30(31):4588-95. doi: 10.1016/j.vaccine.2012.04.096. Epub 2012 May 9.
Despite widespread information about the human papillomavirus (HPV) vaccine, uptake continues to be low (CDC, 2010). HPV vaccine uptake may be maximized by better understanding factors likely to influence parents' decisions to vaccinate their age-recommended children. Previous reviews have summarized barriers and facilitators likely to influence parents' decision to vaccinate their adolescents (mostly daughters) against HPV; however, less attention has been given to summarize and evaluate the methodology. The aim of this study is to systematically review the methodology used in observational studies of HPV vaccine uptake from a parental perspective. A systematic search of Academic Search Premier, CINAHL, ERIC, Medline and PsycInfo to obtain relevant articles after FDA vaccine approval (2006 to present) yielded 446 studies, of which 17 studies were eligible. Results showed the majority of studies were cross-sectional, with random sampling from list-assisted sources being the most common method for data collection. Most studies used convenience samples and relied on parental self-report. Also, the majority of studies explored vaccine initiation, but only a few explored regimen completion and timely completion of vaccine regimen. Given that the effectiveness of the HPV vaccine is based on established recommendations for a three dose regimen within a timely interval, studies on factors likely to influence regimen completion and timely completion of regimen are essential to maximize the effectiveness and public health benefits of the vaccine. Research with more diverse samples, better and increased use of random sampling techniques, and the use of precise and objective measures of vaccine uptake to supplement parental self-report, is necessary to reduce selection and information biases in future studies. Studies to inform on factors likely to influence parents' decisions to vaccinate their sons against HPV are also needed.
尽管人们广泛了解人乳头瘤病毒（HPV）疫苗，但接种率仍然很低（CDC，2010）。通过更好地了解可能影响父母为其推荐年龄的孩子接种疫苗的决策的因素，可以最大限度地提高 HPV 疫苗的接种率。以前的综述总结了可能影响父母为青少年（主要是女儿）接种 HPV 疫苗的障碍和促进因素；然而，对总结和评估方法的关注较少。本研究的目的是系统地综述从父母角度观察 HPV 疫苗接种率的研究中使用的方法。在 FDA 批准疫苗后（2006 年至今），对 Academic Search Premier、CINAHL、ERIC、Medline 和 PsycInfo 进行了系统搜索，以获取相关文章，共获得 446 篇研究，其中 17 篇符合条件。结果表明，大多数研究为横断面研究，最常见的数据收集方法是从名单辅助来源进行随机抽样。大多数研究使用方便样本，并依赖于父母的自我报告。此外，大多数研究都探讨了疫苗的启动，但只有少数研究探讨了方案的完成情况和疫苗方案的及时完成情况。鉴于 HPV 疫苗的有效性基于在及时间隔内完成三剂方案的既定建议，因此研究可能影响方案完成和及时完成方案的因素对于最大限度地提高疫苗的有效性和公共卫生效益至关重要。研究需要更多样化的样本，更好地和更多地使用随机抽样技术，并使用精确和客观的疫苗接种措施来补充父母的自我报告，以减少未来研究中的选择和信息偏倚。还需要研究可能影响父母决定为儿子接种 HPV 疫苗的因素。
