1 Communicable Disease Epidemiology and Immunization Section, Public Health-Seattle & King County, Seattle, WA, USA.
2 Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.
Public Health Rep. 2019 Sep/Oct;134(5):559-566. doi: 10.1177/0033354919867734. Epub 2019 Aug 12.
Uptake and completion of the human papillomavirus (HPV) vaccine series among adolescents are suboptimal in the United States. We examined immunization registry data to determine completion of the 3-dose HPV vaccine series among adolescents in Seattle, Washington, born during 1995-2000 who received ≥1 dose of HPV vaccine.
Immunization data included the administrating facility, which identified adolescents who used school-based health centers (SBHCs) for any HPV vaccine dose. We calculated completion of the 3-dose series at any time and on time by the 13th birthday. We stratified analyses by sex and assessed differences in on-time and any-time completion between users and nonusers of SBHCs.
Overall, 67.9% (8612 of 12 676) of females and 41.8% (3560 of 8521) of males with ≥1 dose of HPV vaccine completed the 3-dose series. Compared with female SBHC nonusers, female SBHC users had 37% higher odds of completing the series at any time (adjusted odds ratio [aOR] = 1.37; 95% CI, 1.19-1.58) and 33% higher odds of completing the series on time (aOR = 1.33; 95% CI, 1.08-1.64). Compared with male SBHC nonusers, male SBHC users had 45% higher odds of completing the series at any time (aOR = 1.45; 95% CI, 1.23-1.70) and 79% higher odds of completing the series on time (aOR = 1.79; 95% CI, 1.11-2.89).
Adolescent SBHC users had higher odds of completing the HPV vaccine series than adolescents who received all doses in traditional health care settings. SBHCs should be leveraged to increase adolescent immunization rates.
人乳头瘤病毒(HPV)疫苗系列在美国青少年中的接种和完成情况并不理想。我们检查了免疫登记数据,以确定在华盛顿州西雅图出生于 1995-2000 年且至少接种过 1 剂 HPV 疫苗的青少年中,有多少人完成了 3 剂 HPV 疫苗系列接种。
免疫数据包括接种机构,该机构确定了在任何 HPV 疫苗剂量中使用学校基础保健中心(SBHC)的青少年。我们按时间计算了任何时间和 13 岁生日时的 3 剂系列完成情况。我们按性别分层分析,并评估了 SBHC 用户和非用户之间按时和任何时间完成的差异。
总体而言,有 67.9%(12676 名中有 8612 名)的女性和 41.8%(8521 名中有 3560 名)的男性至少接种了 1 剂 HPV 疫苗,完成了 3 剂系列接种。与女性 SBHC 非使用者相比,女性 SBHC 使用者在任何时间完成系列接种的可能性要高出 37%(调整后的优势比[aOR] = 1.37;95%置信区间[CI],1.19-1.58),按时完成系列接种的可能性要高出 33%(aOR = 1.33;95%CI,1.08-1.64)。与男性 SBHC 非使用者相比,男性 SBHC 使用者在任何时间完成系列接种的可能性要高出 45%(aOR = 1.45;95%CI,1.23-1.70),按时完成系列接种的可能性要高出 79%(aOR = 1.79;95%CI,1.11-2.89)。
与在传统医疗保健环境中接受所有剂量的青少年相比,青少年 SBHC 用户完成 HPV 疫苗系列接种的可能性更高。应该利用 SBHC 来提高青少年的免疫接种率。