非痴呆老年样本中存在中枢胆碱能缺乏的韦氏成人智力量表剖面图。

Central cholinergic deficiency WAIS profiles in a nondemented aged sample.

作者信息

Tuokko H, Crockett D

出版信息

J Clin Exp Neuropsychol. 1987 Apr;9(2):225-7. doi: 10.1080/01688638708405362.

Abstract

Fuld (1984) described a WAIS profile associated with drug-induced cholinergic deficiency in young adults and dementia of the Alzheimer's type. The frequency of occurrence of this profile was examined in a group of healthy elderly persons who were administered the WAIS. The results of this study suggest that the profile occurs rarely in independently functioning elderly persons, thus lending support to Fuld's findings that the profile may be relatively specific to dementia of the Alzheimer's type. Hypotheses as to the significance of this index of pathology are discussed.

摘要

富尔德（1984年）描述了一种与年轻成年人药物性胆碱能缺乏以及阿尔茨海默型痴呆相关的韦氏成人智力量表（WAIS）剖面图。在一组接受韦氏成人智力量表测试的健康老年人中，对该剖面图出现的频率进行了检查。这项研究的结果表明，这种剖面图在独立生活的老年人中很少出现，从而支持了富尔德的研究结果，即该剖面图可能相对特定于阿尔茨海默型痴呆。文中还讨论了关于这一病理指标意义的假设。