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孕早期经腹绒毛取样——针具重要吗?

First trimester transabdominal chorionic villus sampling--does the needle matter?

作者信息

Wax Joseph R, Cartin Angelina, Chard Renée, Carpenter Molly, Pinette Michael G

机构信息

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine, USA.

出版信息

J Clin Ultrasound. 2012 Sep;40(7):385-8. doi: 10.1002/jcu.21925. Epub 2012 May 15.

DOI:10.1002/jcu.21925
PMID:22585459
Abstract

PURPOSE

To compare first-trimester transabdominal chorionic villus samples (TA-CVS) when obtained by 20-gauge amniocentesis versus lancet needles.

METHODS

This is a retrospective study of all women with viable singleton pregnancies undergoing TA-CVS from 01/01/2009 to 03/31/2011. All CVS were performed by a single operator using a freehand technique and amniocentesis needles from 01/01/2009 to 08/31/2010 and lancet needles from 09/01/2010 to 03/31/2011. All samples were processed by the same laboratory.

RESULTS

There were no differences between groups regarding maternal age, weight, gestational age at CVS, indication for CVS, uterine position, or placental location. Lancet needles were associated with significantly larger samples (median 18 [range 3-40] versus 7 [range 1-33] mg, p < 0.0001), more successful in situ hybridization (96% versus 74.2%, p = 0.03), and faster result reporting (median 7 [range 5-12] versus 9 [range 6-26] days, p = 0.002).

CONCLUSIONS

Needle type may be clinically important when selecting 20-gauge TA-CVS needles.

摘要

目的

比较使用20号羊膜穿刺针与柳叶刀针获取的孕早期经腹绒毛取样(TA - CVS)情况。

方法

这是一项对2009年1月1日至2011年3月31日期间所有接受TA - CVS的单胎活产孕妇的回顾性研究。2009年1月1日至2010年8月31日期间所有的绒毛取样均由同一操作人员采用徒手技术并使用羊膜穿刺针进行,2010年9月1日至2011年3月31日期间则使用柳叶刀针。所有样本均由同一实验室处理。

结果

两组在产妇年龄、体重、绒毛取样时的孕周、绒毛取样指征、子宫位置或胎盘位置方面无差异。柳叶刀针获取的样本显著更大(中位数18 [范围3 - 40] 毫克对7 [范围1 - 33] 毫克,p < 0.0001),原位杂交更成功(96%对74.2%,p = 0.03),结果报告更快(中位数7 [范围5 - 12] 天对9 [范围6 - 26] 天,p = 0.002)。

结论

在选择20号TA - CVS针时,针的类型可能具有临床重要性。

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