Center for Interdisciplinary Salivary Bioscience Research, The Johns Hopkins University, Baltimore, MD, USA.
Biol Res Nurs. 2012 Oct;14(4):347-56. doi: 10.1177/1099800412443892. Epub 2012 May 15.
Analytes and biomarkers present in saliva may provide insight into individual differences in environmental chemical exposures, variation in reproductive hormones, therapeutic and illegal substance use, changes in stress-related physiology, and the immunologic footprints of infectious disease. The wealth of information provided by salivary analytes has the potential to enrich biobehavioral nursing research by enabling researchers to measure these individual differences in the clinic as well as in patients' and participants' everyday social worlds. In this article, the authors provide a roadmap for researchers new to this area who would like to learn more about integrating salivary biospecimens into the next generation of health research. In addition, the authors highlight best practices and strategies to avoid common pitfalls for researchers already engaged in this field.
唾液中的分析物和生物标志物可能有助于深入了解个体在环境化学暴露、生殖激素变化、治疗和非法物质使用、与压力相关的生理变化以及传染病的免疫痕迹方面的差异。唾液分析物提供的丰富信息有可能通过使研究人员能够在临床以及患者和参与者的日常社会环境中测量这些个体差异，从而丰富生物行为护理研究。在本文中，作者为刚接触该领域的研究人员提供了一份路线图，希望他们能更多地了解如何将唾液生物样本整合到下一代健康研究中。此外，作者还强调了已经从事该领域研究的人员需要注意的最佳实践和策略，以避免常见的陷阱。
