Medical Department, University College Hospital Galway, Galway City, Co.Galway, Ireland.
Alcohol Alcohol. 2012 Sep-Oct;47(5):538-44. doi: 10.1093/alcalc/ags054. Epub 2012 May 17.
To investigate the effect of alcohol consumption on the sleep and mood of healthy individuals in a college-based, mixed gender population.
Forty-seven individuals participated in this study, of whom 33 consumed alcohol and were included in the analysis. Sleep quality was objectively recorded using actigraphy. Subjects completed a daily sleep diary and bipolar Profile of Mood States Questionnaire, recording the subjective perception of sleep quality and waking mood respectively.
Mean self-reported alcohol consumption among the drinkers was 84.6 ml ethanol/night. Mean total sleep time for those who consumed less than the mean reported intake was significantly reduced on alcohol. This reduction in sleep time was associated with increased wakefulness in the second half of the night, a truncated sleeping period and increased waking fatigue. This rebound wakefulness could not be demonstrated in those who consumed higher than the mean intake, though these individuals also reported increased waking fatigue.
These results add weight to the clinical evidence that ethanol should not be used as a hypnotic due to its potential to affect both the quantity and quality of sleep. The finding that total sleep time is reduced on low doses of alcohol is novel and may arise from measuring sleep in an environment other than the sleep laboratory.
在以大学生为基础的混合性别人群中，研究饮酒对健康个体睡眠和情绪的影响。
47 名个体参与了这项研究，其中 33 名饮酒者被纳入分析。使用活动记录仪客观记录睡眠质量。受试者分别完成每日睡眠日记和双相心境状态问卷，记录主观睡眠质量和醒来时的情绪感知。
饮酒者的自我报告平均酒精摄入量为 84.6 毫升/每晚。与低于平均摄入量的饮酒者相比，睡眠时间明显减少。这种睡眠时间的减少与夜间后半段的觉醒增加、睡眠时间缩短和醒来时疲劳增加有关。在摄入高于平均水平的饮酒者中，无法证明这种反弹性觉醒，尽管这些人也报告说醒来时疲劳增加。
这些结果为临床证据增加了份量，即由于乙醇可能影响睡眠的数量和质量，因此不应将其用作催眠剂。在低剂量饮酒时总睡眠时间减少的发现是新颖的，可能源于在睡眠实验室以外的环境中测量睡眠。
