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[中性粒细胞不影响在扩散盒中体内培养的粒细胞祖细胞的克隆生长]

[Neutrophils do not affect clonal growth of granulocyte progenitor cells cultured in vivo in diffuse chambers].

作者信息

Hansz J, Wozny T, Jurkowiecka J, Sawiński K, Mensah O W

机构信息

Kliniki Hematologii Instytutu Chorób Wewnetrznych Akademii Medycznej w Poznaniu.

出版信息

Acta Haematol Pol. 1990 Jan-Jun;21(1):66-71.

PMID:2260410
Abstract

The effect of polymorphonuclear leukocytes on the growth of granulocytic progenitors in the diffusion chamber culture (CFU-dG) has been studied. It has been shown that peripheral blood neutrophils do not affect the myeloid colony formation in this culture system. The inhibition of CFU-dG growth, observed in the presence of peripheral blood leukocytes was dependent on prostaglandins release from monocytes.

摘要

已研究了多形核白细胞对扩散室培养中粒细胞祖细胞(CFU-dG)生长的影响。结果表明,外周血中性粒细胞在该培养系统中不影响髓系集落形成。在外周血白细胞存在的情况下观察到的CFU-dG生长抑制取决于单核细胞释放的前列腺素。

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