Sleep Disorder Center Ramathibodi Hospital, Pulmonary and Critical Care Unit, Medicine Department, Mahidol University, Bangkok, Thailand.
Sleep Med. 2012 Jun;13(6):656-62. doi: 10.1016/j.sleep.2012.02.008. Epub 2012 May 17.
To compare clinical manifestations and polysomnographic data of sleep-disordered breathing (SDB) in younger (less than 30 years old) versus older premenopausal women.
A cohort of 420 premenopausal women diagnosed with SDB in a university sleep clinic during a 5-year period underwent systematic collection of clinical and polysomnographic variables.
One-hundred and fifteen (27.4%) women were younger than 30 (mean 24.5 ± 3.5 years), while 305 (72.6%) were older than 30 (mean 39.5 ± 5.7 years). The younger premenopausal women had less severe SDB with a trend towards upper-airway resistance syndrome. Despite similar daytime consequences, snoring was less common in the younger group. Both groups of premenopausal women frequently had insomnia and nasal abnormalities or craniofacial-deficiency.
Recognizing the different clinical features and understanding the different polysomnographic presentation of SDB in young premenopausal women are crucial to detecting and treating this syndrome.
比较年轻（<30 岁）与年长（绝经前）女性睡眠呼吸紊乱（SDB）的临床表现和多导睡眠图数据。
在大学睡眠诊所的 5 年期间，对诊断为 SDB 的 420 名绝经前女性进行了系统的临床和多导睡眠图变量采集。
115 名（27.4%）女性年龄小于 30 岁（平均 24.5 ± 3.5 岁），305 名（72.6%）年龄大于 30 岁（平均 39.5 ± 5.7 岁）。年轻的绝经前女性 SDB 程度较轻，上气道阻力综合征的趋势更为明显。尽管白天的后果相似，但在年轻组中，打鼾的情况并不常见。两组绝经前女性都经常有失眠、鼻部异常或颅面缺陷。
认识到年轻绝经前女性 SDB 的不同临床特征和多导睡眠图表现有助于检测和治疗该综合征。
