Department of Nephrology, Dialysis, Transplantation, University of Liège, CHU Sart Tilman, 4000 Liège, Belgium.
Am J Kidney Dis. 2012 Aug;60(2):299-307. doi: 10.1053/j.ajkd.2012.03.019. Epub 2012 May 19.
Anorexia nervosa is a common psychiatric disorder that disproportionately affects adolescents and young adults and is associated with high rates of morbidity and mortality. Anorexia nervosa can affect the kidney in numerous ways, including increased rates of acute kidney injury and chronic kidney disease, electrolyte abnormalities, and nephrolithiasis. Additionally, the diagnosis and treatment of anorexia nervosa-associated kidney diseases are challenging, reflecting complications such as refeeding syndrome, as well as the limitations of serum creatinine level in this population to estimate kidney function and the psychosocial challenges inherent with treating systemic manifestations of psychiatric conditions. In this review, we discuss kidney diseases and kidney-associated conditions that occur in individuals with anorexia nervosa, summarizing many of the challenges in treating patients with this disease.
神经性厌食症是一种常见的精神疾病，在青少年和年轻成年人中发病率较高，与高发病率和死亡率相关。神经性厌食症可以通过多种方式影响肾脏，包括急性肾损伤和慢性肾脏病的发生率增加、电解质异常和肾结石。此外，神经性厌食症相关肾脏疾病的诊断和治疗具有挑战性，反映出一些并发症，如再喂养综合征，以及血清肌酐水平在该人群中估计肾功能的局限性，以及治疗精神疾病全身表现所固有的心理社会挑战。在这篇综述中，我们讨论了神经性厌食症患者中出现的肾脏疾病和与肾脏相关的疾病，总结了治疗这种疾病患者所面临的许多挑战。
