Malania oleifera 中的二苯甲酮糖苷和表儿茶素衍生物。

Benzophenone glycosides and epicatechin derivatives from Malania oleifera.

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, PR China.

出版信息

Fitoterapia. 2012 Sep;83(6):1068-71. doi: 10.1016/j.fitote.2012.05.006. Epub 2012 May 17.

DOI:10.1016/j.fitote.2012.05.006

PMID:22609684

Abstract

A new benzophenone C-glycoside, malaferin A (1), and two new epicatechin derivatives, malaferin B (2) and malaferin C (3), together with five known compounds were isolated from Malania oleifera. In addition, (-)-epicatechin-3-O-benzoate (6) was isolated for the first time from a natural resource. Structures of 1-3 were determined on the basis of their spectroscopic methods, including 1D and 2D NMR techniques. All of the compounds were evaluated for anti-HIV activities.

摘要

从 Malania oleifera 中分离得到一个新的苯并二酮 C-糖苷马拉菲林 A（1），两个新的表儿茶素衍生物马拉菲林 B（2）和马拉菲林 C（3），以及 5 个已知化合物。此外，(-)-表儿茶素-3-O-苯甲酸酯（6）也是首次从天然资源中分离得到。根据光谱学方法，包括 1D 和 2D NMR 技术，确定了 1-3 的结构。所有化合物均进行了抗 HIV 活性评价。