Anaerobe Laboratory, Department of Microbiology, Institute of Biomedical Science, University of São Paulo, Brazil.
Anaerobe. 2012 Aug;18(4):381-5. doi: 10.1016/j.anaerobe.2012.04.008. Epub 2012 May 17.
The occurrence of Porphyromonas gulae, Porphyromonas macacae, Fusobacterium nucleatum and Fusobacterium canifelinum in subgingival plaque from dogs with and without periodontitis as well as their antimicrobial susceptibility were evaluated. From 50 dogs with periodontitis were identified 38 P. gulae, 8 P. macacae, 26 F. nucleatum and 15 F. canifelinum, and from 50 dogs without periodontitis were identified 15 P. gulae, 12 F. nucleatum and 11 F. canifelinum. All strains were susceptible to most of the antibiotics tested, however, different resistance rates to clarithromycin, erythromycin and metronidazole among strains were observed. The role of P. gulae, P. macacae, F. nucleatum and F. canifelinum in periodontal disease of household pets needs to be defined to a better prevention and treatment of the canine periodontitis.
检测了伴放线放线杆菌、猕猴链球菌、具核梭杆菌和坏死梭杆菌在有和无牙周炎犬的龈下菌斑中的发生情况及其对抗菌药物的敏感性。在 50 只患有牙周炎的犬中鉴定出 38 株伴放线放线杆菌、8 株猕猴链球菌、26 株具核梭杆菌和 15 株坏死梭杆菌,在 50 只无牙周炎的犬中鉴定出 15 株伴放线放线杆菌、12 株具核梭杆菌和 11 株坏死梭杆菌。所有菌株对大多数测试的抗生素均敏感,但不同菌株对克拉霉素、红霉素和甲硝唑的耐药率存在差异。需要进一步明确伴放线放线杆菌、猕猴链球菌、具核梭杆菌和坏死梭杆菌在家养宠物牙周病中的作用,以更好地预防和治疗犬牙周炎。