Hardham John, Dreier Kimberly, Wong Jason, Sfintescu Cornelia, Evans Richard T
Pfizer Inc., Veterinary Medicine Research and Development, 301 Henrietta Street, Kalamazoo, MI 49001, USA.
Vet Microbiol. 2005 Mar 20;106(1-2):119-28. doi: 10.1016/j.vetmic.2004.12.018.
The etiology of human periodontal disease has been the focus of considerable research, yet relatively little is known about the causative agents of companion animal periodontitis. In humans, Porphyromonas gingivalis, a black-pigmented anaerobic bacteria (BPAB), has been implicated as the primary periopathogen. It has been demonstrated that BPAB are also found in companion animal periodontal pockets. While some animal BPAB have been individually identified, a study to identify the most frequently isolated subgingival BPAB has not been completed using genetic tools. The objective of this work was to identify the types and relative frequencies of pigmented anaerobic bacteria found in the periodontal pockets of dogs. Porphyromonas salivosa, Porphyromonas denticanis (a novel species) and Porphyromonas gulae were found to be the most frequently isolated BPAB associated with canine periodontitis.
人类牙周病的病因一直是大量研究的焦点，但对于伴侣动物牙周炎的致病因素却知之甚少。在人类中，牙龈卟啉单胞菌，一种黑色色素厌氧菌（BPAB），被认为是主要的牙周病原体。已经证明，BPAB也存在于伴侣动物的牙周袋中。虽然已经分别鉴定出一些动物BPAB，但尚未使用基因工具完成一项鉴定最常分离出的龈下BPAB的研究。这项工作的目的是确定在狗的牙周袋中发现的色素厌氧菌的类型和相对频率。唾液卟啉单胞菌、犬齿卟啉单胞菌（一个新物种）和龈卟啉单胞菌被发现是与犬牙周炎相关的最常分离出的BPAB。
