Endoscopy Center, Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Surg Endosc. 2012 Nov;26(11):3267-72. doi: 10.1007/s00464-012-2336-y. Epub 2012 May 19.
The aim of this study was to investigate the management and treatment for complications during and after peroral endoscopic myotomy (POEM) for patients suffering from esophageal achalasia (EA).
The data of 119 cases of EA patients who underwent POEM from October 2010 to July 2011 and the complications that arose during the operation, after the operation, and during follow-up were analyzed.
Complications that occurred during the operation included cutaneous emphysema (22.7 %, 27/119) and pneumothorax (2.5 %, 3/119). Postoperative complications included pneumothorax (25.2 %, 30/119), subcutaneous emphysema (55.5 %, 66/119), mediastinal emphysema (29.4 %, 35/119), delayed hemorrhage (0.8 %, 1/119), pleural effusion (48.7 %, 58/119), minor inflammation or segmental atelectasis of the lungs (49.6 %, 59/119), and gas under diaphragm or aeroperitoneum (39.5 %, 47/119). Complications that occurred during follow-up included one case of difficulty eating caused by the stricture of mucosa and one case of dehiscence at the mouth of the tunnel created during surgery, with food retention. No deaths occurred. All complications were resolved through traditional treatment. No additional surgery was needed.
Complications arising during and after POEM should be treated quickly and can be resolved by using traditional treatment. POEM can be expected to become the preferred treatment for EA.
本研究旨在探讨经口内镜肌切开术(POEM)治疗食管失弛缓症(EA)患者术中及术后并发症的处理方法。
回顾性分析 2010 年 10 月至 2011 年 7 月期间 119 例行 POEM 治疗的 EA 患者的临床资料,分析术中、术后及随访期间出现的并发症。
术中并发症包括皮下气肿(22.7%,27/119)和气胸(2.5%,3/119)。术后并发症包括气胸(25.2%,30/119)、皮下气肿(55.5%,66/119)、纵隔气肿(29.4%,35/119)、迟发性出血(0.8%,1/119)、胸腔积液(48.7%,58/119)、肺部轻微炎症或节段性肺不张(49.6%,59/119)、膈下游离气体或气腹(39.5%,47/119)。随访期间发生的并发症包括 1 例因黏膜狭窄导致的进食困难和 1 例隧道口撕裂导致食物潴留,均经传统治疗治愈。无死亡病例。所有并发症均经传统治疗治愈,无需进一步手术。
POEM 术中及术后并发症应及时处理,传统治疗可有效解决。POEM 有望成为 EA 的首选治疗方法。