Department of Gastroenterology, 71213The Second Hospital of Hebei Medical University, Hebei Key Laboratory of Gastroenterology, 71213Hebei Institute of Gastroenterology, 71213Hebei Clinical Research Centre for Digestive Diseases, Shijiazhuang, Hebei Province, China.
Department of Nutrition, Shijiazhuang Maternity and Child Healthcare Hospital, Shijiazhuang, Hebei Province, China.
J Int Med Res. 2022 Nov;50(11):3000605221135475. doi: 10.1177/03000605221135475.
Peroral endoscopic myotomy (POEM) has been shown to be an effective treatment for achalasia and with few adverse events. Only a few cases of delayed bleeding have been described. This current case report describes a patient with delayed bleeding in the submucosal tunnel on the eighth day after POEM. The patient was a 21-year-old woman with a 4-month history of dysphagia, vomiting and excessive weight loss. Achalasia was diagnosed according to her symptoms, barium oesophagogram, oesophageal manometry and endoscopy examination. POEM was performed by an experienced operator. On the eighth day after POEM, the patient suddenly developed continuous haematemesis presented with vomiting of fresh blood and melena. An emergency exploratory esophagogastroduodenoscopy was performed. A large number of blood clots were found at the wound and a long haematoma was found along the lining of the submucosal tunnel. Re-entry into the submucosal tunnel and exposure of the haemorrhagic site was attempted but failed because of severe submucosal tissue adhesion. An emergency angiography was undertaken and haemostasis was achieved with superselective arterial microcoil embolization.
经口内镜下肌切开术(POEM)已被证明是治疗贲门失弛缓症的有效方法,且不良事件极少。仅描述了少数几例迟发性出血病例。本病例报告描述了 1 例 POEM 后第 8 天发生黏膜下隧道迟发性出血的患者。该患者为 21 岁女性,有 4 个月吞咽困难、呕吐和明显体重减轻病史。根据其症状、钡餐食管造影、食管测压和内镜检查诊断为贲门失弛缓症。POEM 由经验丰富的术者施行。POEM 后第 8 天,患者突然出现持续呕血,表现为呕鲜血和黑便。紧急行食管胃十二指肠探查镜检查,发现伤口处有大量血凝块,黏膜下隧道沿线有长形血肿。再次进入黏膜下隧道并试图暴露出血部位,但由于黏膜下组织严重粘连而失败。紧急行血管造影,通过超选择性动脉微线圈栓塞实现止血。