USDA Economic Research Service, Washington, DC 20024, USA.
J Public Health (Oxf). 2012 Dec;34(4):489-97. doi: 10.1093/pubmed/fds032. Epub 2012 May 18.
Childhood vaccination may protect children's nutritional status and lead to improved child growth in developing countries. This study evaluates the effect of India's childhood vaccination program Universal Immunization Program (UIP) on the growth of children <4 years of age.
Regression models were estimated to examine the effect of UIP on vaccination status and children's anthropometric outcomes, as well as to test whether UIP's effect was uniform across various subpopulations of Indian children.
UIP increased height-for-age and weight-for-age among children. This effect constituted a 22-25% reduction in the height-for-age deficit and a 15% reduction in the weight-for-age deficit of the average child. The program appears to have had no effect on other anthropometric indicators or vaccination status. UIP also led to differential changes in anthropometry and vaccination status, based on differences in wealth, maternal education and scheduled-caste status.
UIP led to improved child growth. This suggests that vaccination programs-in addition to being a major intervention for reducing child mortality-might be considered a tool for mitigating undernutrition in developing countries. This study also adds to the growing evidence that childhood vaccination programs are high-return investments because they produce long-term health benefits for children.
儿童期疫苗接种可以保护儿童的营养状况,并促进发展中国家儿童的生长发育。本研究评估了印度儿童期疫苗接种计划(UIP)对<4 岁儿童生长的影响。
回归模型用于检验 UIP 对疫苗接种状况和儿童人体测量学结果的影响,并检验 UIP 的效果是否在印度儿童的不同亚群中具有一致性。
UIP 增加了儿童的身高与年龄比和体重与年龄比。这种影响使平均儿童的身高与年龄比缺陷减少了 22-25%,体重与年龄比缺陷减少了 15%。该计划似乎对其他人体测量指标或疫苗接种状况没有影响。UIP 还导致了基于财富、母亲教育和在册种姓地位差异的人体测量和疫苗接种状况的差异变化。
UIP 导致了儿童生长的改善。这表明,疫苗接种计划——除了是减少儿童死亡率的主要干预措施之外——也可以被视为减轻发展中国家营养不良的一种手段。本研究还增加了越来越多的证据表明,儿童期疫苗接种计划是高回报的投资,因为它们为儿童带来了长期的健康益处。