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表现为肛瘘和直肠腺癌的骶前畸胎癌：一例独特病例报告及文献复习

Presacral teratocarcinoma presenting as anal fistula and rectal adenocarcinoma: a unique case presentation and literature review.

作者信息

Ho S P, Wang J S, Tseng H H, King T M

机构信息

Department of Pathology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

出版信息

Case Rep Oncol. 2012 Jan;5(1):84-90. doi: 10.1159/000336579. Epub 2012 Feb 10.

DOI:10.1159/000336579
PMID:22611366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3355654/
Abstract

Somatic malignancy arising from presacral or retroperitoneal primary teratoma is extremely rare. We report the case of a 37-year-old male patient with adenocarcinoma of respiratory type arising from primary presacral teratoma, but which first presented as anal fistula and rectal adenocarcinoma. The two tumors show the same morphology and immunophenotype (CK7-CK20+CDx2+). Malignant adenocarcinoma transformations from the normal respiratory epithelium are also found. To the best of our knowledge, this is the second case of respiratory type adenocarcinoma arising from primary presacral mature cystic teratoma.

摘要

骶前或腹膜后原发性畸胎瘤引发的躯体恶性肿瘤极为罕见。我们报告了一例37岁男性患者，其原发性骶前畸胎瘤引发了呼吸型腺癌，但最初表现为肛瘘和直肠腺癌。这两种肿瘤具有相同的形态和免疫表型（CK7-CK20+CDx2+）。同时也发现了从正常呼吸上皮发生的恶性腺癌转化。据我们所知，这是第二例由原发性骶前成熟囊性畸胎瘤引发的呼吸型腺癌病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9c2/3355654/8b8a6911f8af/cro-0005-0084-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9c2/3355654/6339b3459b99/cro-0005-0084-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9c2/3355654/3fac5c7eaad9/cro-0005-0084-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9c2/3355654/8b8a6911f8af/cro-0005-0084-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9c2/3355654/6339b3459b99/cro-0005-0084-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9c2/3355654/3fac5c7eaad9/cro-0005-0084-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9c2/3355654/8b8a6911f8af/cro-0005-0084-g03.jpg

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本文引用的文献

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A case of mucinous adenocarcinoma arising from retroperitoneal teratoma treated with chemoradiation.一例源于腹膜后畸胎瘤的黏液性腺癌，经放化疗治疗。
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J Gynecol Oncol. 2009 Jun;20(2):126-8. doi: 10.3802/jgo.2009.20.2.126. Epub 2009 Jun 29.
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