Blum L M, Carenzo E F, Rieders F
National Medical Services, Inc., Willow Grove, Pennsylvania 19090.
J Anal Toxicol. 1990 Sep-Oct;14(5):285-7. doi: 10.1093/jat/14.5.285.
An instrumental high-performance thin-layer chromatographic (HPTLC) technique for the determination of lysergic acid diethylamide (LSD) in urine was developed. Before chromatographic separation, a single-step extraction with alkaline wash is performed. The procedure can detect less than 1 microgram LSD/L urine. Results of HPTLC determination are compared with those from a radioimmunoassay (RIA) procedure.