Department of Preventive Medicine, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Infect Dis Clin North Am. 2012 Jun;26(2):293-307. doi: 10.1016/j.idc.2012.03.001. Epub 2012 Apr 17.
Tegumentary leishmaniases are caused by approximately 15 species of protozoa of the genus Leishmania. They prevail in tropical and subtropical areas of the Old and New World but human mobility also makes them a medical problem in nonendemic areas. Clinical manifestations may comprise cutaneous and mucocutaneous forms that may be localized, disseminated, or diffuse in distribution and may differ in Old and New World leishmaniases. Diagnosis and treatment vary according to the clinical manifestations, geographic area, and Leishmania species involved. This article highlights the diversity and complexity of tegumentary leishmaniases, which are worsened by human immunodeficiency virus/Leishmania coinfection.
皮肤利什曼病是由大约 15 种利什曼原虫引起的。它们流行于旧世界和新世界的热带和亚热带地区，但人类的流动性也使它们成为非流行地区的一个医学问题。临床表现可能包括皮肤和黏膜形式，可能局限、扩散或弥漫分布，在旧世界和新世界利什曼病中可能有所不同。诊断和治疗因临床表现、地理区域和涉及的利什曼原虫种类而异。本文重点介绍了皮肤利什曼病的多样性和复杂性，人类免疫缺陷病毒/利什曼原虫合并感染使其更加恶化。
