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内镜超声引导下的抗肿瘤药物。

Endoscopic ultrasound-guided antitumor agents.

作者信息

Nakai Yousuke, Chang Kenneth J

机构信息

Division of Gastroenterology and Hepatology, H.H. Chao Comprehensive Digestive Disease Center, University of California, Irvine, 101 The City Drive, Orange, CA 92868, USA.

出版信息

Gastrointest Endosc Clin N Am. 2012 Apr;22(2):315-24, x. doi: 10.1016/j.giec.2012.04.014. Epub 2012 May 3.

DOI:10.1016/j.giec.2012.04.014
PMID:22632953
Abstract

The development of linear-array endoscopic ultrasonography (EUS), with its real-time guidance of needle advancement, changed EUS from a diagnostic procedure to an interventional procedure. EUS-guided fine-needle injection (EUS-FNI) is an attractive minimally invasive delivery system with potential applications in local (intratumoral) and combination therapy against esophageal and pancreatic cancers. The evidence of the feasibility of EUS-FNI of antitumor agents has been expanding with promising results.

摘要

线性阵列超声内镜检查(EUS)的发展,凭借其对针推进的实时引导,将EUS从一种诊断程序转变为一种介入程序。EUS引导下的细针注射(EUS-FNI)是一种有吸引力的微创给药系统,在针对食管癌和胰腺癌的局部(瘤内)及联合治疗中具有潜在应用价值。抗肿瘤药物EUS-FNI可行性的证据一直在不断增加,结果令人鼓舞。

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