Seoul, Korea From IMI Plastic Surgery and the Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine.
Plast Reconstr Surg. 2012 Jun;129(6):1359-1368. doi: 10.1097/PRS.0b013e31824ecbb0.
Recently, fat injection has been performed across the globe and has several advantages. However, there have not been many studies regarding the relationship between complications and contributing factors. The authors analyzed factors present when complications occurred during fat injections into the face.
A retrospective chart review was performed for 62 patients who had moderate complications among the 1261 persons who had received full-face fat injection between April of 2004 and July of 2008. Complications included chronic edema, calcification, fibrosis, acne, headache, dysesthesia, drooping, and irregularity.
There were no differences among the first, second, and third injection groups regarding age, body weight, height, or body mass index. However, there were statistically significant differences in injection amount and complication occurrence time (p < 0.0001). There were statistically significant differences in injection amount and complication occurrence time between the fresh and frozen fat (p < 0.0001). There were statistically significant differences regarding age, injection amount, and complication occurrence time according to the complication groups (p < 0.0001). There was also a difference between timing of the injection and the complication frequency (Fisher's exact test, p < 0.0001) and between fat status and the complication frequency (Fisher's exact test, p = 0.005).
Chronic edema, calcification, fibrosis, acne, headache, dysesthesia, drooping, and irregularity after full-face fat injection were observed as moderate complications. Although further study will be needed for the effective analysis of complications according to the number of injection or fat status, the authors found significant differences in age, complication occurrence time, and injection amount between some complication groups.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, II.
最近，脂肪注射已在全球范围内进行，并具有多种优势。然而，关于并发症与相关因素之间的关系的研究并不多。作者分析了面部脂肪注射过程中发生并发症时存在的因素。
对 2004 年 4 月至 2008 年 7 月期间接受过全脸脂肪注射的 1261 人中出现中度并发症的 62 例患者进行了回顾性图表审查。并发症包括慢性水肿、钙化、纤维化、痤疮、头痛、感觉异常、下垂和不规则。
在第一、第二和第三注射组之间，年龄、体重、身高或体重指数没有差异。然而，在注射量和并发症发生时间方面存在统计学显著差异（p < 0.0001）。新鲜脂肪和冷冻脂肪之间在注射量和并发症发生时间方面存在统计学显著差异（p < 0.0001）。根据并发症组，在年龄、注射量和并发症发生时间方面存在统计学显著差异（p < 0.0001）。注射时间和并发症频率之间也存在差异（Fisher 精确检验，p < 0.0001），脂肪状况和并发症频率之间也存在差异（Fisher 精确检验，p = 0.005）。
全脸脂肪注射后观察到慢性水肿、钙化、纤维化、痤疮、头痛、感觉异常、下垂和不规则等中度并发症。尽管需要进一步研究根据注射次数或脂肪状况有效分析并发症，但作者发现一些并发症组在年龄、并发症发生时间和注射量方面存在显著差异。
临床问题/证据水平：风险，II。
