伊朗病理学家对前列腺腺癌进行Gleason评分的观察者间/观察者内可重复性
Inter/intra-observer reproducibility of Gleason scoring in prostate adenocarcinoma in Iranian pathologists.
作者信息
Abdollahi Alireza, Meysamie Alipasha, Sheikhbahaei Sara, Ahmadi Ali, Moradi-Tabriz Hedieh, Bakhshandeh Mohammadreza, Hosseinzadeh Hassan
机构信息
Department of Pathology, Imam Khomeini Teaching Hospital, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Urol J. 2012 Spring;9(2):486-90.
PURPOSE
To measure the level of inter/intra-observer reproducibility among pathologists as far as Gleason scoring of adenocarcinoma of the prostate is concerned.
MATERIALS AND METHODS
A total of 101 prostate biopsy slides, diagnosed with adenocarcinoma of the prostate by five pathologists from different education centers, were exposed to Gleason scoring. Two months later, the slides were re-examined by three of the same pathologists. Thereafter, the kappa was calculated for the data provided in the first and second reports of each pathologist and compared between pathologists.
RESULTS
Inter-observer reproducibility was inappropriate, but intra-observer diagnostic reproducibility was almost perfect with a corresponding percentage of agreement of 85.2%.
CONCLUSION
The inter-observer reproducibility was poor.
目的
就前列腺腺癌的Gleason评分而言，测量病理学家之间观察者间/观察者内的可重复性水平。
材料与方法
来自不同教育中心的五位病理学家诊断为前列腺腺癌的总共101张前列腺活检切片接受Gleason评分。两个月后，其中三位病理学家对这些切片进行重新检查。此后，针对每位病理学家的第一份和第二份报告中提供的数据计算kappa值，并在病理学家之间进行比较。
结果
观察者间的可重复性不理想，但观察者内的诊断可重复性几乎完美，相应的一致率为85.2%。
结论
观察者间的可重复性较差。
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