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居住在佛罗里达州迈阿密-戴德县的海地人、非裔美国人和西班牙裔在艾滋病治疗反应方面的差异。

Disparities in HIV-treatment responses between Haitians, African Americans, and Hispanics living in Miami-Dade County, Florida.

作者信息

Colasanti Jonathan, Nguyen Linda, Kiem JoAnn Tjin Kon, Deeb Khaled, Jayaweera Dushyantha

机构信息

Jay Weiss Center for Social Medicine and Health Equity, University of Miami–Miller School of Medicine (UM-MSM), Miami, FL 33136, USA.

出版信息

J Health Care Poor Underserved. 2012 Feb;23(1):179-90. doi: 10.1353/hpu.2012.0004.

DOI:10.1353/hpu.2012.0004
PMID:22643470
Abstract

BACKGROUND

Studies evaluating response to treatment with Highly Active Antiretroviral Therapy (HAART) fail to examine Haitian patients living in the U.S. as a distinct group.

METHODS

This study was designed to determine the effectiveness of HAART in Haitians compared with other minority groups. We conducted a retrospective cohort study of HIV patients from two clinics. The cohort included 96 Hispanics, 60 African Americans, and 49 Haitians, after reviewing a total of 891 charts.

RESULTS

At 96 weeks, fewer Haitians (58.5%) achieved a suppressed viral load than African American (74.1%) or Hispanic (82.8%) patients (p=.021). Median CD4 counts at baseline were lowest among Haitians, with 158 cells/mm3, compared with African Americans, 176 cells/mm3 and Hispanics, 199 cells/mm3.

CONCLUSIONS

Haitians are not doing as well on HAART as other groups. This may be explained by linguistic, cultural, or other barriers that are not currently addressed by the health care system in the United States.

摘要

背景

评估高效抗逆转录病毒疗法(HAART)治疗反应的研究未能将居住在美国的海地患者作为一个独特群体进行考察。

方法

本研究旨在确定与其他少数群体相比,HAART对海地人的有效性。我们对来自两家诊所的HIV患者进行了一项回顾性队列研究。在查阅了总共891份病历后,该队列包括96名西班牙裔、60名非裔美国人和49名海地人。

结果

在96周时,实现病毒载量抑制的海地人(58.5%)比非裔美国人(74.1%)或西班牙裔患者(82.8%)更少(p = 0.021)。海地人基线时的CD4细胞计数中位数最低,为158个细胞/立方毫米,相比之下,非裔美国人为176个细胞/立方毫米,西班牙裔为199个细胞/立方毫米。

结论

海地人接受HAART治疗的效果不如其他群体。这可能是由于语言、文化或其他障碍所致,而美国医疗保健系统目前并未解决这些问题。

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