Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Sci China Life Sci. 2012 May;55(5):434-43. doi: 10.1007/s11427-012-4318-7. Epub 2012 May 27.
Cataract is the single largest contributor to blindness in the world, with the disease having a strong genetic component. In recent years the Eph family of receptor tyrosine kinases has been identified as a key regulator in lens clarity. In this review we discuss the roles of the Eph receptors in lens biology and cataract development.
白内障是全球导致失明的首要原因，这种疾病具有很强的遗传成分。近年来，Eph 受体酪氨酸激酶家族已被确定为晶状体透明度的关键调节因子。在这篇综述中，我们讨论了 Eph 受体在晶状体生物学和白内障发生发展中的作用。
