El Hage Rawad, El Hage Zaher, Moussa Elie, Baddoura Rafic, Theunynck Denis, Jacob Christophe
Laboratoire de physiologie et de biomécanique de la performance motrice, Université de Balamand, Al Koura, Liban.
J Med Liban. 2012 Jan-Mar;60(1):30-6.
The aim of this study was to compare femoral shaft and intertrochanteric geometry in overweight and normal weight adolescent girls.
This study included 22 overweight (Body mass index (BMI) > 25 kg/m2) adolescent girls (15.4 +/- 2.4 years old) and 20 maturation-matched (15.2 +/- 1.9 years old) controls (BMI < 25 kg/m2). Body composition and BMD were assessed by dual-energy X-ray absorptiometry (DXA). To evaluate bone geometry, DXA scans were analyzed at the femoral shaft and the intertrochanteric region by the Hip Structure Analysis (HSA) program. Cross-sectional area (CSA), an index of axial compression strength, section modulus (Z), an index of bending strength, cross-sectional moment of inertia (CSMI), cortical thickness (CT) and buckling ratio (BR) were measured from bone mass profiles. Lean mass, body weight, fat mass and BMI were higher in overweight girls compared to controls (p < 0.001). CSA, Z, CSMI and CT were higher in overweight girls compared to controls (p < 0.05) at the two regions (femoral shaft and intertrochanteric). After adjustment for maturation index (years since menarche), CSA, Z, CSMI and CT of the intertrochanteric region and CSA of the femoral shaft were higher in overweight girls compared to controls (p < 0.05). After adjustment for either body weight, lean mass or BMI, using a one-way analysis of covariance (ANCOVA), there were no differences between the two groups (overweight and controls) regarding the HSA variables (CSA, CSMI, Z, CT and BR) at the femoral shaft and the intertrochanteric.
This study suggests that overweight adolescent girls have greater indices of bone axial and bending strength in comparison to controls at the intertrochanteric after adjustment for maturation index.
本研究旨在比较超重和正常体重青春期女孩的股骨干和转子间几何结构。
本研究纳入了22名超重（体重指数（BMI）>25kg/m²）的青春期女孩（15.4±2.4岁）和20名成熟度匹配（15.2±1.9岁）的对照组女孩（BMI<25kg/m²）。采用双能X线吸收法（DXA）评估身体成分和骨密度。为评估骨骼几何结构，通过髋关节结构分析（HSA）程序对股骨干和转子间区域的DXA扫描进行分析。从骨量剖面图中测量截面积（CSA，轴向抗压强度指标）、截面模量（Z，抗弯强度指标）、截面惯性矩（CSMI）、皮质厚度（CT）和屈曲比（BR）。与对照组相比，超重女孩的瘦体重、体重、脂肪量和BMI更高（p<0.001）。在两个区域（股骨干和转子间），超重女孩的CSA、Z、CSMI和CT均高于对照组（p<0.05）。在调整成熟指数（初潮后年数）后，超重女孩转子间区域的CSA、Z、CSMI和CT以及股骨干的CSA均高于对照组（p<0.05）。在调整体重、瘦体重或BMI后，使用单因素协方差分析（ANCOVA），两组（超重组和对照组）在股骨干和转子间的HSA变量（CSA、CSMI、Z、CT和BR）方面没有差异。
本研究表明，在调整成熟指数后，超重青春期女孩转子间的骨轴向和抗弯强度指标高于对照组。
