Laboratoire de Physiologie et de Biomécanique de la Performance Motrice, Université de Balamand, Al Koura, Lebanon.
J Bone Miner Metab. 2011 Nov;29(6):691-8. doi: 10.1007/s00774-011-0267-7. Epub 2011 Apr 7.
The influence of being overweight on bone strength in adolescents remains controversial. The aim of this study was to compare hip bone strength indices in overweight and control adolescent boys using hip structure analysis (HSA). This study included 25 overweight adolescent boys [body mass index (BMI) >25 kg/m(2)] and 31 maturation-matched controls (BMI <25 kg/m(2)). Body composition and bone mineral density were assessed by dual-energy X-ray absorptiometry (DXA). To evaluate hip bone strength, DXA scans were analyzed at femoral neck, intertrochanteric, and femoral shaft by the HSA program. Cross-sectional area (CSA), an index of axial compression strength, section modulus (Z), an index of bending strength, cross-sectional moment of inertia (CSMI), cortical thickness (CT), and buckling ratio (BR) were measured from bone mass profiles. Body weight, lean mass, fat mass, and BMI were higher in overweight boys compared to controls (P < 0.001). CSA, CSMI, and Z of the three sites (femoral neck, intertrochanteric, and femoral shaft) were higher in overweight boys compared to controls (P < 0.01). BR was not significantly different between the two groups at the three sites. After adjustment for either body weight, BMI, or fat mass, using a one-way analysis of covariance, there were no differences between the two groups regarding the HSA variables (CSA, Z, CSMI, CT, and BR). After adjusting for lean mass, overweight boys displayed higher values of femoral shaft CSA, CSMI, and Z in comparison to controls (P < 0.05). In conclusion, this study suggests that overweight adolescent boys have greater indices of bone axial and bending strength in comparison to controls at the femoral neck, the intertrochanteric, and the femoral shaft.
超重对青少年骨骼强度的影响仍存在争议。本研究旨在使用髋关节结构分析（HSA）比较超重和对照组青少年男孩的髋骨强度指数。本研究纳入了 25 名超重青少年男孩（BMI＞25kg/m²）和 31 名成熟匹配的对照组（BMI＜25kg/m²）。通过双能 X 射线吸收法（DXA）评估身体成分和骨密度。为了评估髋骨强度，通过 HSA 程序对股骨颈、转子间和股骨干进行 DXA 扫描分析。从骨质量曲线中测量了横截面积（CSA）、轴向压缩强度指标、截面模数（Z）、弯曲强度指标、截面惯性矩（CSMI）、皮质厚度（CT）和屈曲比（BR）。超重男孩的体重、瘦体重、脂肪量和 BMI 均高于对照组（P＜0.001）。与对照组相比，超重男孩的三个部位（股骨颈、转子间和股骨干）的 CSA、CSMI 和 Z 均较高（P＜0.01）。两组在三个部位的 BR 无显著差异。使用单向方差分析协方差调整体重、BMI 或脂肪量后，两组在 HSA 变量（CSA、Z、CSMI、CT 和 BR）方面无差异。调整瘦体重后，与对照组相比，超重男孩的股骨干 CSA、CSMI 和 Z 值更高（P＜0.05）。综上所述，本研究表明，与对照组相比，超重青少年男孩的股骨颈、转子间和股骨干的骨轴向和弯曲强度指标更高。
