Laboratoire de physiologie et de biomécanique de la performance motrice, Université de Balamand, Al Koura, Lebanon.
Osteoporos Int. 2012 May;23(5):1593-600. doi: 10.1007/s00198-011-1754-3. Epub 2011 Sep 1.
The aim of this study was to compare hip bone strength indices in obese, overweight, and normal-weight adolescent boys using hip structure analysis. After adjusting for weight, obese boys displayed lower intertrochanteric cross-sectional moment of inertia and femoral shaft cross-sectional moment of inertia and section modulus in comparison to normal-weight and overweight boys. This study suggests that in obese adolescent boys, femoral shaft bending strength is not adapted to the increased body weight.
The influence of being obese or overweight on bone strength in adolescents remains controversial. The main aim of this study was to compare hip bone strength indices in obese, overweight, and normal-weight adolescent boys using hip structure analysis. The second aim of this study was to explore the influence of lean mass and fat mass on hip bone strength indices in the same population.
This study included 70 adolescent boys (25 obese, 25 normal weight, and 20 overweight). The three groups (obese, overweight, and normal weight) were matched for maturity (Tanner stage) and age. Body composition and bone mineral density (BMD) were assessed by dual-energy X-ray absorptiometry (DXA). To evaluate hip bone strength, DXA scans were analyzed at the femoral neck (FN), the intertochanteric (IT), and the femoral shaft (FS) by the Hip Structure Analysis (HSA) program. Cross-sectional area (CSA), an index of axial compression strength, section modulus (Z), an index of bending strength, and cross-sectional moment of inertia (CSMI), an index of structural rigidity were measured from bone mass profiles.
Body weight, lean mass, fat mass and BMI were significantly higher in obese and overweight boys in comparison to normal-weight boys (P < 0.05). Total hip (TH) BMD and femoral neck (FN) BMD were significantly higher in obese and overweight boys in comparison to normal-weight boys (P < 0.05). After adjusting for age or maturation index, obese and overweight boys displayed significantly higher TH and FN BMD, CSA, CSMI, and Z of the three sites (FN, IT, and FS) in comparison to normal-weight boys (P < 0.05). However, after adjusting for weight, obese boys displayed significantly lower IT CSMI and FS CSMI and Z in comparison to normal-weight and overweight boys (P < 0.05).
This study suggests that in obese adolescent boys, intertrochanteric structural rigidity and femoral shaft structural rigidity and bending strength are not adapted to the increased body weight.
本研究旨在通过髋关节结构分析比较肥胖、超重和正常体重青少年男孩的髋骨强度指数。在调整体重后，与正常体重和超重男孩相比，肥胖男孩的股骨颈和股骨骨干的横向和纵向截面惯性矩以及截面模数均较低。本研究表明，在肥胖青少年男孩中，股骨的弯曲强度并未适应体重的增加。
肥胖或超重对青少年骨骼强度的影响仍存在争议。本研究的主要目的是通过髋关节结构分析比较肥胖、超重和正常体重青少年男孩的髋骨强度指数。本研究的第二个目的是探讨在同一人群中，瘦体重和脂肪量对髋骨强度指数的影响。
本研究纳入了 70 名青少年男孩（肥胖 25 名，正常体重 25 名，超重 20 名）。三组（肥胖、超重和正常体重）的成熟度（Tanner 分期）和年龄相匹配。通过双能 X 线吸收法（DXA）评估身体成分和骨密度（BMD）。为了评估髋骨强度，使用 Hip Structure Analysis（HSA）程序对股骨颈（FN）、股骨粗隆间（IT）和股骨骨干（FS）的 DXA 扫描进行分析。从骨质量曲线中测量了横截面积（CSA）、轴向压缩强度指标、截面模数（Z）、弯曲强度指标和结构刚性的截面惯性矩（CSMI）。
与正常体重男孩相比，肥胖和超重男孩的体重、瘦体重、脂肪量和 BMI 显著更高（P<0.05）。与正常体重男孩相比，肥胖和超重男孩的全髋（TH）和股骨颈（FN）BMD 显著更高（P<0.05）。在调整年龄或成熟指数后，与正常体重男孩相比，肥胖和超重男孩的 TH 和 FN 的 BMD、CSA、CSMI 和三个部位（FN、IT 和 FS）的 Z 显著更高（P<0.05）。然而，在调整体重后，与正常体重和超重男孩相比，肥胖男孩的 IT CSMI 和 FS CSMI 和 Z 显著更低（P<0.05）。
本研究表明，在肥胖的青少年男孩中，股骨粗隆间的结构刚性和股骨骨干的结构刚性和弯曲强度并未适应体重的增加。
