肠道微生物对人乳寡糖的消耗。
Human milk oligosaccharide consumption by intestinal microbiota.
机构信息
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
出版信息
Clin Microbiol Infect. 2012 Jul;18 Suppl 4(0 4):12-5. doi: 10.1111/j.1469-0691.2012.03863.x.
Abstract
Human milk oligosaccharides (HMO) constitute the third most abundant class of molecules in breast milk. Since infants lack the enzymes required for milk glycan digestion, this group of carbohydrates passes undigested to the lower part of the intestinal tract, where they can be consumed by specific members of the infant gut microbiota. We review proposed mechanisms for the depletion and metabolism of HMO by two major bacterial genera within the infant intestinal microbiota, Bifidobacterium and Bacteroides.
摘要
人乳寡糖（HMO）是母乳中含量第三丰富的分子类别。由于婴儿体内缺乏消化乳聚糖所需的酶，这组碳水化合物未经消化就会进入肠道下段，在那里被婴儿肠道微生物群的特定成员消耗。我们综述了婴儿肠道微生物群中的两个主要细菌属双歧杆菌属和拟杆菌属消耗和代谢 HMO 的可能机制。
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