Faculty of Medicine, Department of Cardiology, Bozok University, Yozgat, Turkey.
Angiology. 2013 May;64(4):300-3. doi: 10.1177/0003319712448247. Epub 2012 May 30.
We evaluated the association between serum uric acid (SUA) and atrial fibrillation (AF) in patients with chronic heart failure (HF). Totally, 363 patients with chronic HF were included in the study. Of all, 78 patients had AF and 285 patients were in normal sinus rhythm. Serum uric acid was significantly increased in patients with AF compared with patients in normal sinus rhythm (P < .05). Comparing patients with AF and normal sinus rhythm, we found that age was significantly higher in patients group with AF. Echocardiographic parameters including ejection fraction, left atrial diameter, left ventricle end-diastolic diameter, and left ventricle end-diastolic volume were also significantly higher in patients with AF compared with patients in normal sinus rhythm. We have shown that patients with AF have significantly higher SUA and this was independently associated with AF in patients with ischemic HF.
我们评估了血清尿酸（SUA）与慢性心力衰竭（HF）患者心房颤动（AF）之间的关系。共有 363 例慢性 HF 患者纳入研究。其中，78 例患者患有 AF，285 例患者窦性心律正常。与窦性心律正常的患者相比，AF 患者的血清尿酸明显升高（P<.05）。比较 AF 患者和窦性心律正常的患者，我们发现 AF 患者的年龄明显更高。超声心动图参数，包括射血分数、左心房直径、左心室舒张末期直径和左心室舒张末期容积，在 AF 患者中也明显高于窦性心律正常的患者。我们已经表明，AF 患者的 SUA 明显更高，并且这与缺血性 HF 患者的 AF 独立相关。
