Northumbria Healthcare NHS Foundation Trust, Department of Elderly Medicine, North Tyneside General Hospital, Rake Lane, North Shields, NE29 8NH, UK.
Expert Rev Neurother. 2012 Jun;12(6):661-6. doi: 10.1586/ern.12.52.
The vast majority of patients with Parkinson's disease (PD) in sub-Saharan Africa are undiagnosed and untreated with impaired quality of life and markedly increased mortality rates. PD is a progressive neurodegenerative disorder that becomes increasingly common as people age. Diagnosis remains predominantly clinical based on motor symptoms: tremor, rigidity, bradykinesia and postural instability. In developed countries, it is well recognized and very few patients will not be diagnosed and treated. However, in developing countries, such as those in sub-Saharan Africa, evidence suggests that most patients are undiagnosed, and even if they are diagnosed, they do not have access to sustainable, affordable, drug treatment and medical supervision. There is a lack of awareness, both within the general population and also among healthcare professionals, and many patients seek help from traditional healers. Even if they are diagnosed, treatment is often too expensive, and supplies are sporadic. There is a great need to increase awareness of PD within the general population and the fact that the symptoms are treatable. Education of healthcare workers about PD is also important, but a major challenge is there are few doctors and even fewer neurologists. Awareness raising and training will be to no avail, unless the problem of an affordable, reliable supply of drug treatment can be tackled.
撒哈拉以南非洲绝大多数帕金森病(PD)患者未被诊断和治疗,生活质量受损,死亡率明显升高。PD 是一种进行性神经退行性疾病,随着年龄的增长,其发病率越来越高。诊断主要基于运动症状,即震颤、僵硬、运动迟缓以及姿势不稳。在发达国家,PD 已被广泛认识,很少有患者未被诊断和治疗。然而,在发展中国家,如撒哈拉以南非洲国家,有证据表明,大多数患者未被诊断,即使被诊断,他们也无法获得可持续、负担得起的药物治疗和医疗监督。无论是在普通人群中,还是在医疗保健专业人员中,对此病的认识都很缺乏,许多患者向传统治疗师寻求帮助。即使他们被诊断出来,治疗费用通常也很昂贵,而且供应也不稳定。非常有必要提高普通人群对 PD 的认识,让他们知道这种疾病的症状是可以治疗的。对医疗保健工作者进行 PD 教育也很重要,但一个主要的挑战是医生和神经科医生都很少。除非能够解决负担得起、可靠的药物治疗供应问题,否则提高认识和培训将无济于事。