Mokaya Jolynne, Dotchin Catherine L, Gray William K, Hooker Juzar, Walker Richard W
Kenyatta National Hospital Nairobi Kenya.
Northumbria Healthcare NHS Foundation Trust North Tyneside General Hospital North Shields United Kingdom.
Mov Disord Clin Pract. 2016 Jan 9;3(4):376-381. doi: 10.1002/mdc3.12294. eCollection 2016 Jul-Aug.
There is a dearth of knowledge about the availability and affordability of the different drug treatments for Parkinson's disease (PD) across sub-Saharan Africa (SSA). We aimed to determine the availability and affordability of drugs for treating PD in Kenya.
A facility-based survey was conducted in selected medicine outlets (pharmacies) in what were formerly the headquarter towns of the eight provinces of Kenya. We used the World Health Organization/Health Action International methodology to obtain data for drugs used to treat PD. Unit price for each drug was obtained.
Forty-eight outlets were visited in total, six in each of Kenya's eight provinces. Levodopa (L-dopa) was available in only 24 (50.0%) outlets. Only one public pharmacy sold l-dopa (14 were private and nine were other types of outlet). Ergot-derived dopamine agonists (DAs) and anticholinergics were available in 37 and 35 outlets, respectively. Monoamine-oxidase inhibitors, non-ergot-derived DAs, and catechol--methyl transferase inhibitors were available in four, two and zero outlets, respectively. Mean cost of 100 l-dopa tablets was $48.2, though costs varied widely (range, $28.2-$82.4). Only five outlets considered l-dopa affordable, all of which sold 100 tablets for less than $31.
There is a lack of availability of PD drugs in Kenya, particularly in public pharmacies, where costs are generally lower. Few pharmacists consider the drugs available to be affordable. If PD is to be effectively managed in Kenya, then strategies are needed to increase the availability and affordability of medication.
关于撒哈拉以南非洲(SSA)地区治疗帕金森病(PD)的不同药物疗法的可及性和可负担性,目前知识匮乏。我们旨在确定肯尼亚治疗PD药物的可及性和可负担性。
在肯尼亚八个省份以前的省会城镇中选定的药品销售点(药店)进行了一项基于机构的调查。我们采用世界卫生组织/国际卫生行动组织的方法来获取治疗PD所用药物的数据。获取了每种药物的单价。
总共走访了48个销售点,肯尼亚的八个省份各有6个。左旋多巴(L -多巴)仅在24个(50.0%)销售点有售。只有一家公立药店出售L -多巴(14家为私立药店,9家为其他类型的销售点)。麦角衍生的多巴胺激动剂(DAs)和抗胆碱能药物分别在37个和35个销售点有售。单胺氧化酶抑制剂、非麦角衍生的DAs和儿茶酚 - 甲基转移酶抑制剂分别在4个、2个和0个销售点有售。100片L -多巴片剂的平均成本为48.2美元,不过成本差异很大(范围为28.2美元至82.4美元)。只有5个销售点认为L -多巴价格可承受,所有这些销售点100片的售价均低于31美元。
肯尼亚缺乏PD药物,尤其是在成本通常较低的公立药店。很少有药剂师认为现有药物价格可承受。如果要在肯尼亚有效管理PD,那么需要制定策略来提高药物供应和可负担性。