Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Department of Geography and Environment, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Endocrinol Diabetes Metab. 2024 Jul;7(4):e00491. doi: 10.1002/edm2.491.
Metabolic syndrome (MetS) is a group of medical conditions that elevate the chances of developing cardiovascular disease, stroke and Type 2 diabetes. This study aimed to determine the frequency and contributing risk factors of MetS in adults from Bangladesh.
In this cross-sectional study, 653 individuals (470 males and 183 females) were randomly selected to participate. Fasting blood samples were collected and analysed using standard methods to measure biochemical parameters. MetS was defined on the basis of NCEP-ATP III guidelines, and multivariate logistic regression analyses were conducted to identify factors associated with MetS.
The prevalence of MetS was 19.7% in the healthy control group, 70.2% in the hypertensive group and 46.8% in the diabetic group. Overall, there was no significant difference in the prevalence of MetS between males (45%) and females (45.9%). The participants who had both hypertension and diabetes had the highest prevalence of MetS at 77.3%. Both males and females showed an increased trend in the prevalence of MetS and its components as they aged, except for WC in males (p < 0.01 for all cases). The 46-55 age group in males had a higher prevalence of MetS (68%), whereas the >55 age group in females had a prevalence of 73.9%. The most common component of MetS was low levels of HDL-C, which affected over 80% of the studied sample. According to the logistic regression analyses, age, BMI, hypertension and diabetes were significantly associated with MetS in both genders.
This study found a high prevalence of MetS in Bangladeshi adults. Several factors are significantly associated with the risk of MetS. It is crucial to consider the varying prevalence rates of MetS by age and gender as well as its different components while providing health guidance and support.
代谢综合征（MetS）是一组增加心血管疾病、中风和 2 型糖尿病发病风险的医学病症。本研究旨在确定孟加拉国成年人中 MetS 的发生频率及其相关风险因素。
本横断面研究随机选取了 653 名个体（470 名男性和 183 名女性）参与。采集空腹血样，采用标准方法分析以测量生化参数。MetS 依据 NCEP-ATP III 指南定义，采用多变量逻辑回归分析鉴定与 MetS 相关的因素。
在健康对照组、高血压组和糖尿病组中，MetS 的患病率分别为 19.7%、70.2%和 46.8%。总体而言，男性（45%）和女性（45.9%）之间 MetS 的患病率无显著差异。同时患有高血压和糖尿病的患者 MetS 患病率最高，为 77.3%。男性和女性的 MetS 及其各组分的患病率均随年龄增长呈上升趋势，除男性 WC 外（所有病例均 p<0.01）。男性 46-55 岁年龄组的 MetS 患病率较高（68%），而女性>55 岁年龄组的患病率为 73.9%。MetS 最常见的组分是 HDL-C 水平低，影响了超过 80%的研究样本。根据逻辑回归分析，年龄、BMI、高血压和糖尿病在两性中均与 MetS 显著相关。
本研究发现孟加拉国成年人中 MetS 的患病率较高。多种因素与 MetS 的发病风险显著相关。在提供健康指导和支持时，考虑 MetS 的不同年龄和性别患病率以及其不同组分至关重要。
