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犬颌骨特发性骨坏死的病例系列及综述

A case series and review of canine idiopathic osteonecrosis of the jaw.

作者信息

Rossi Amy, Anderson Jamie G

机构信息

BluePearl Tacoma, Tacoma, WA, United States.

School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States.

出版信息

Front Vet Sci. 2025 May 27;12:1614645. doi: 10.3389/fvets.2025.1614645. eCollection 2025.

DOI:10.3389/fvets.2025.1614645
PMID:40496918
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12148862/
Abstract

Idiopathic osteonecrosis of the jaw in dogs is a rare disease. Research into human osteonecrosis of the jaw has increased considerably in recent years revealing numerous underlying risk factors and comorbidities. The goal of this case series was to evaluate similar risk factors and comorbidities in dogs. The medical records from 10 cases were retrospectively reviewed for patient signalment, diagnostic results and treatment. Most cases had either cone beam or conventional computed tomography performed which allowed a detailed evaluation of maxillofacial structures. In this cohort, lesions had a predilection for the caudal maxilla and ipsilateral zygomatic arch and dental surgery did not always precede development of lesions. More cases and additional diagnostics will be needed to uncover the etiology of this disease.

摘要

犬特发性颌骨骨坏死是一种罕见疾病。近年来,对人类颌骨骨坏死的研究显著增加,揭示了众多潜在风险因素和合并症。本病例系列的目的是评估犬类中类似的风险因素和合并症。对10例病例的医疗记录进行回顾性分析,以了解患者的特征、诊断结果和治疗情况。大多数病例都进行了锥形束CT或传统CT检查,从而能够对颌面结构进行详细评估。在这个队列中,病变好发于上颌骨后部和同侧颧弓,并且病变的发生并不总是在牙科手术后。需要更多病例和进一步的诊断来揭示该疾病的病因。

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本文引用的文献

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Osteonecrosis of the femoral head in post-COVID-19 patients: a retrospective comparative study.新冠疫情后患者的股骨头坏死:一项回顾性比较研究
J Orthop Surg Res. 2025 Apr 10;20(1):362. doi: 10.1186/s13018-025-05657-8.
2
Prevention and Management of Osteoradionecrosis in Patients With Head and Neck Cancer Treated With Radiation Therapy: ISOO-MASCC-ASCO Guideline.头颈部癌症放射治疗患者的放射性骨坏死的预防和管理:ISOO-MASCC-ASCO 指南。
J Clin Oncol. 2024 Jun 1;42(16):1975-1996. doi: 10.1200/JCO.23.02750. Epub 2024 May 1.
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Oral Surgery and Osteoradionecrosis in Patients Undergoing Head and Neck Radiation Therapy: An Update of the Current Literature.
头颈部放疗患者的口腔外科手术与放射性骨坏死:当前文献综述
Biomedicines. 2023 Dec 18;11(12):3339. doi: 10.3390/biomedicines11123339.
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Pathophysiology of Medication-Related Osteonecrosis of the Jaw-A Minireview.颌骨药物相关性骨坏死的病理生理学——一篇综述
JBMR Plus. 2023 Jun 22;7(8):e10785. doi: 10.1002/jbm4.10785. eCollection 2023 Aug.
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Atraumatic osteonecrosis of the humeral head: pathophysiology and current concepts of evaluation and treatment.肱骨头无创伤性骨坏死:病理生理学及评估与治疗的当前概念
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Medication-Related Osteonecrosis: Why the Jawbone?药物相关性骨坏死:为何是颌骨?
Dent J (Basel). 2023 Apr 23;11(5):109. doi: 10.3390/dj11050109.
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Review of Osteoradionecrosis of the Jaw: Radiotherapy Modality, Technique, and Dose as Risk Factors.颌骨放射性骨坏死综述:放疗方式、技术及剂量作为风险因素
J Clin Med. 2023 Apr 21;12(8):3025. doi: 10.3390/jcm12083025.
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Osteonecrosis of the Jaw.颌骨骨坏死
Dent J (Basel). 2023 Jan 9;11(1):23. doi: 10.3390/dj11010023.
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Osteoradionecrosis of the jaw: A mini review.颌骨放射性骨坏死:一篇综述
Front Oral Health. 2022 Jul 28;3:980786. doi: 10.3389/froh.2022.980786. eCollection 2022.
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Medication-Related Osteonecrosis of the Jaw (MRONJ): A Review of Pathophysiology, Risk Factors, Preventive Measures and Treatment Strategies.药物相关性颌骨坏死(MRONJ):病理生理学、危险因素、预防措施及治疗策略综述
Saudi Dent J. 2022 Mar;34(3):202-210. doi: 10.1016/j.sdentj.2022.01.003. Epub 2022 Jan 19.