Department of Neurosurgery, Poitiers University School of Medicine, Poitiers, France.
Neurosurgery. 2012 Sep;71(3):E757-62; discussion E763. doi: 10.1227/NEU.0b013e318260fd8f.
There is large variation in the success of decompressive surgery for pudendal neuralgia (PN), the most chronic, disabling form of perineal pain. We attempt to determine whether spinal cord stimulation using new-generation multicolumn leads could form part of the treatment algorithm for refractory PN.
A man with PN that was unresponsive to conventional treatment demonstrated a neuropathic component and had a negative response to nerve infiltrations (so he was not indicated for decompressive surgery) and a positive response to perianal transcutaneous electrical nerve stimulation and was implanted with a 16-contact surgical lead at the level of conus medullaris, allowing multicolumn stimulation. Using transverse combinations, it was possible to obtain 100% paresthesia over the perineal area without unwanted dorsal root stimulation. Perineal and radicular pain was successfully relieved for up to 12 months (80% and 60% reduction in the visual analogue scale scores, respectively), with an improvement in all quality of life domains and a reduction in drug consumption.
Spinal cord stimulation using a 16-contact lead may be a viable therapeutic option for patients with refractory PN for whom decompressive surgery is contraindicated.
阴部神经痛(PN)是最慢性和致残性的会阴疼痛形式,减压手术的成功率存在很大差异。我们试图确定使用新一代多柱导联的脊髓刺激是否可以成为难治性 PN 治疗方案的一部分。
一名患有 PN 的男性对常规治疗无反应,表现出神经病理性成分,对神经浸润无反应(因此不适合减压手术),对肛周经皮电神经刺激有反应,并在马尾水平植入 16 触点手术导联,允许多柱刺激。使用横交组合,有可能在不引起背根刺激的情况下使会阴部获得 100%的感觉异常。会阴和神经根疼痛成功缓解长达 12 个月(视觉模拟评分分别降低 80%和 60%),所有生活质量领域均得到改善,药物消耗减少。
对于不适合减压手术的难治性 PN 患者,使用 16 触点导联的脊髓刺激可能是一种可行的治疗选择。