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干扰素γ诱导蛋白-10 在既往结核感染和疾病患儿中的浓度。

Interferon gamma-induced protein-10 concentrations in children with previous tuberculosis infections and disease.

机构信息

Child and Reproductive Health Group, Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.

出版信息

Pediatr Infect Dis J. 2012 Oct;31(10):1089-91. doi: 10.1097/INF.0b013e3182611152.

DOI:10.1097/INF.0b013e3182611152
PMID:22653490
Abstract

Interferon gamma-induced protein-10 is a diagnostic test for tuberculosis infection. There is no information on its concentrations over time. Interferon gamma-induced protein-10 was evaluated in 72 children formerly treated or in former contact with tuberculosis using Quantiferon Gold in-tube. Cases and contacts had similar interferon gamma-induced protein-10 concentrations. Concentrations varied with the tuberculin and interferon gamma release tests' concordance or discordance, and were independent of time.

摘要

干扰素诱导蛋白-10 是一种用于诊断结核感染的检测方法。目前尚无关于其随时间变化的浓度的信息。本研究使用 QuantiFERON Gold in-tube 对 72 例曾接受或接触过结核病治疗的儿童进行了干扰素诱导蛋白-10 的评估。病例组和接触组的干扰素诱导蛋白-10 浓度相似。浓度随结核菌素和干扰素γ释放试验的一致性或不一致性而变化,且与时间无关。

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Evaluation of the filter paper IP-10 tests in school children after exposure to tuberculosis: a prospective cohort study with a 4-year follow-up.评价接触结核分枝杆菌后在校儿童滤纸片干扰素γ释放试验:一项具有 4 年随访的前瞻性队列研究。
BMJ Open. 2012 Dec 4;2(6). doi: 10.1136/bmjopen-2012-001751. Print 2012.