Shaw Colette M, Madoff David C
Division of Diagnostic Imaging, Interventional Radiology Section, The University of Texas M. D. Anderson Cancer Center, Houston, Texas.
Semin Intervent Radiol. 2011 Jun;28(2):156-61. doi: 10.1055/s-0031-1280655.
Portal vein thrombosis (PVT) is an uncommon, but potentially devastating complication of portal vein embolization (PVE). Its occurrence relates to both local and systemic risk factors. In the setting of PVE, precipitating factors include injury to the vessel wall and reduced portal flow. Contributory factors include portal hypertension, hypercoagulopathy, inflammatory processes, malignancy, pregnancy, oral contraceptive use, and asplenia. The goal of therapy is to prevent thrombus progression and lyse existing clot. Hepatectomy is impossible if adequate recanalization has not occurred and/or overt portal hypertension develops. The mechanisms for thrombus development, its diagnosis, management, and prognosis are discussed.
门静脉血栓形成（PVT）是门静脉栓塞术（PVE）一种罕见但可能具有毁灭性的并发症。其发生与局部和全身危险因素均有关。在PVE情况下，促发因素包括血管壁损伤和门静脉血流减少。促成因素包括门静脉高压、高凝状态、炎症过程、恶性肿瘤、妊娠、口服避孕药的使用以及无脾。治疗的目标是防止血栓进展并溶解现有血栓。如果未发生充分的再通和/或出现明显的门静脉高压，则无法进行肝切除术。本文讨论了血栓形成的机制、其诊断、管理及预后。
