Chan Chung-Hung, Ngoh Gek-Cheng, Yusoff Rozita
University of Malaya, Department of Chemical Engineering, Kuala Lumpur, Malaysia.
Pharmacogn Rev. 2012 Jan;6(11):22-8. doi: 10.4103/0973-7847.95854.
A study has been conducted with the aim to provide researchers with general information on anti diabetic extracts based on relevant research articles collected from 34 reliable medical journals. The study showed that Asian and African continents have 56% and 17% share of the worldwide distribution of therapeutic herbal plants, respectively. In Asia, India and China are the leading countries in herbal plants research, and there has been an increase in medicinal research on plants extract for diabetes treatment since 1995 in these regions. The information collected shows that plant leaves are about 20% more favorable for storing active ingredients, as compared to other parts of herbal plants. A brief review on the extraction techniques for the mentioned parts is also included. Furthermore, the acting mechanisms for the anti diabetic activity were described, and the related active ingredients were identified. The findings reveal that most of the anti diabetic research is focused on the alteration of glucose metabolism to prevent diabetes.
一项研究旨在根据从34种可靠医学期刊收集的相关研究文章,为研究人员提供有关抗糖尿病提取物的一般信息。该研究表明,亚洲和非洲大陆在全球治疗性草药植物分布中所占份额分别为56%和17%。在亚洲,印度和中国是草药植物研究的领先国家,自1995年以来,这些地区对用于糖尿病治疗的植物提取物的医学研究有所增加。收集到的信息表明,与草药植物的其他部分相比,植物叶子储存活性成分的适宜性要高约20%。文中还简要回顾了上述部分的提取技术。此外,描述了抗糖尿病活性的作用机制,并鉴定了相关活性成分。研究结果表明,大多数抗糖尿病研究集中在改变葡萄糖代谢以预防糖尿病。