The complex and multifactorial nature of Alzheimer's disease.
作者信息
Alkadhi Karim, Eriksen Jason
出版信息
Curr Neuropharmacol. 2011 Dec;9(4):586. doi: 10.2174/157015911798376235.
Abstract
摘要
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本文引用的文献
1
Asymptomatic Alzheimer's disease: a prodrome or a state of resilience?
Curr Alzheimer Res. 2011 Jun;8(4):330-5. doi: 10.2174/156720511795745348.
2
The Nun study: clinically silent AD, neuronal hypertrophy, and linguistic skills in early life.
Neurology. 2009 Sep 1;73(9):665-73. doi: 10.1212/WNL.0b013e3181b01077. Epub 2009 Jul 8.
3
Neuronal hypertrophy in asymptomatic Alzheimer disease.
J Neuropathol Exp Neurol. 2008 Jun;67(6):578-89. doi: 10.1097/NEN.0b013e3181772794.
4
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.
Science. 2002 Jul 19;297(5580):353-6. doi: 10.1126/science.1072994.
5
Alzheimer's disease.
BMJ. 1998 Feb 7;316(7129):446-8. doi: 10.1136/bmj.316.7129.446.
6
Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease.
Neurology. 1984 Jul;34(7):939-44. doi: 10.1212/wnl.34.7.939.
7
Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported.
JAMA. 1989 Nov 10;262(18):2551-6.
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