目前对神经胶质细胞对衰老中枢神经系统疾病反应的理解。
Current understanding of the glial response to disorders of the aging CNS.
作者信息
Barker Roger A, Cicchetti Francesca
机构信息
Department of Clinical Neuroscience, Cambridge Centre for Brain Repair, University of Cambridge Cambridge, UK.
出版信息
Front Pharmacol. 2012 May 28;3:95. doi: 10.3389/fphar.2012.00095. eCollection 2012.
Abstract
In this special issue of Frontiers in Pharmacology, we have asked leading experts to comment and review the evidence that inflammatory cells play a leading role in the pathological processes underlying neurodegenerative disorders. We now seek to draw these various observations together into a conclusion, with the hope that this will inform further work in this area and result in the identification of new therapeutic targets that will have a disease modifying effect.
摘要
在《药理学前沿》的这一特刊中，我们邀请了顶尖专家对炎症细胞在神经退行性疾病潜在病理过程中起主导作用的证据进行评论和综述。我们现在试图将这些不同的观察结果汇总成一个结论，希望这将为该领域的进一步研究提供参考，并促成新治疗靶点的发现，这些靶点将具有疾病修饰作用。
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