Otolaryngology - Head & Neck Surgery;
Can J Infect Dis Med Microbiol. 2011 Summer;22(2):49-51. doi: 10.1155/2011/261519.
To retrospectively review trends in clindamycin resistance among Staphylococcus aureus head and neck abscesses between January 2000 and June 2008.
Between January 2000 and June 2008, inpatient and out-patient S aureus isolates were reviewed for antibiotic susceptibility. In particular, cultures from 153 abscesses in the head and neck region were assessed for clindamycin and methicillin resistance patterns.
Annual clindamycin resistance rates for all S aureus isolates, and specifically for S aureus head and neck abscesses, revealed concerning levels of clindamycin and methicillin resistance. After 2002, the mean clindamycin resistance rate in head and neck abscesses was approximately 27%. The number of new cases of methicillin-resistant S aureus per year increased from four cases in 2000 to 44 cases in 2007.
Antibiotic resistance should be considered following failed empirical therapy of head and neck abscesses with clindamycin.
回顾 2000 年 1 月至 2008 年 6 月期间金黄色葡萄球菌头颈部脓肿克林霉素耐药的趋势。
在 2000 年 1 月至 2008 年 6 月期间，对住院和门诊的金黄色葡萄球菌分离株进行了抗生素敏感性检测。特别地，对头颈部 153 个脓肿的培养物进行了克林霉素和甲氧西林耐药模式的评估。
所有金黄色葡萄球菌分离株的年度克林霉素耐药率，以及特别是金黄色葡萄球菌头颈部脓肿的克林霉素耐药率，显示出令人担忧的克林霉素和甲氧西林耐药水平。2002 年后，头颈部脓肿的平均克林霉素耐药率约为 27%。每年耐甲氧西林金黄色葡萄球菌的新发病例数从 2000 年的 4 例增加到 2007 年的 44 例。
对于用克林霉素治疗失败的头颈部脓肿，应考虑抗生素耐药性。
