Bulut T, Yilmazlar A, Yavascaoglu B, Sarisozen B
J Child Orthop. 2011 Jun;5(3):179-85. doi: 10.1007/s11832-011-0337-3. Epub 2011 Mar 24.
We aimed to investigate the effects on post-operative pain of local anaesthetic administration via a catheter placed into the operation site in patients who were undergoing upper and lower extremity paediatric orthopaedic surgery.
In this randomised, double-blind and placebo study, 40 ASA I-II patients aged between 1 and 12 years were randomly allocated into two groups: study group (Group S: 0.2 ml/kg, 0.5% bupivacaine, n = 20) and control group (Group C: 0.2 ml/kg, serum physiologic, n = 20). Before the fascia was closed by the surgical team, the solution previously prepared by the chief nurse was injected into the subfascial soft tissue with the syringe as the "injected dose" of serum physiologic or bupivacaine. After the closure, 0.2 ml/kg (1 mg/kg) bupivacaine or saline was instillated as the "first instillated dose" into the surgical area via the catheter. Pain scores were recorded at 0, 1, 2, 4, 8, 12, 24 and 48 h post-operatively. Patients were administered 0.75 mg/kg meperidine intramuscularly post-operatively to equalise the pain scores.
No statistically significant difference was found between Group S and Group C in terms of demographic and other data and pain scores in the post-anaesthesia care unit, while a statistically significant decrease was found at 2, 4, 8, 12, 24 and 48 h in Group S and at 1, 2 and 4 h in Group C based on pain scores in the post-anaesthesia care unit (P < 0.05). A statistically significant decreasing pain score was found at 4, 8, 12, 24 and 48 h in Group S (P < 0.05).
The local anaesthetic administered via a catheter implanted in the surgical field may provide long-term and efficient post-operative analgesia.
我们旨在研究在接受小儿上下肢骨科手术的患者中,通过置于手术部位的导管给予局部麻醉药对术后疼痛的影响。
在这项随机、双盲、安慰剂对照研究中,40例年龄在1至12岁之间的美国麻醉医师协会(ASA)I-II级患者被随机分为两组:研究组(S组:0.2 ml/kg,0.5%布比卡因,n = 20)和对照组(C组:0.2 ml/kg,生理盐溶液,n = 20)。在手术团队关闭筋膜前,由护士长预先配制的溶液用注射器作为生理盐溶液或布比卡因的“注射剂量”注入筋膜下软组织。关闭后,通过导管将0.2 ml/kg(1 mg/kg)布比卡因或生理盐水作为“首次注入剂量 ”滴入手术区域。术后0、1、2、4、8、12、24和48小时记录疼痛评分。术后给予患者0.75 mg/kg哌替啶肌肉注射以使疼痛评分均衡。
S组和C组在人口统计学和其他数据以及麻醉后护理单元的疼痛评分方面无统计学显著差异,而基于麻醉后护理单元的疼痛评分,S组在术后2、4、8、12、24和48小时以及C组在术后1、2和4小时疼痛评分有统计学显著降低(P < 0.05)。S组在术后4、8、12、24和48小时疼痛评分有统计学显著降低(P < 0.05)。
通过植入手术区域的导管给予局部麻醉药可提供长期有效的术后镇痛。