Nakayama K
Department of Microbiology, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
Gene. 1990 Nov 30;96(1):149-50. doi: 10.1016/0378-1119(90)90357-w.
The gene (sod) encoding the superoxide dismutase (SOD) of the obligately anaerobic bacterium Bacteroides gingivalis was cloned. The amino acid (aa) sequence of the SOD, deduced from the nucleotide sequence of the sod gene, basically resembled that of known Fe-SODs. However, the aa sequence of the B. gingivalis SOD was found to be intermediate between those of Fe-SOD and Mn-SOD in a limited region around the putative second ligand, where major differences between the aa sequences of Fe-SOD and Mn-SOD are known to exist.
对专性厌氧菌牙龈卟啉单胞菌中编码超氧化物歧化酶(SOD)的基因(sod)进行了克隆。根据sod基因的核苷酸序列推导得出的SOD氨基酸(aa)序列,与已知的铁超氧化物歧化酶(Fe-SOD)基本相似。然而,在假定的第二个配体周围的有限区域内,发现牙龈卟啉单胞菌SOD的氨基酸序列处于Fe-SOD和锰超氧化物歧化酶(Mn-SOD)之间,已知Fe-SOD和Mn-SOD的氨基酸序列在该区域存在主要差异。