沙眼衣原体宫颈感染治疗后是否需要进行治愈检测？
Is a test of cure necessary following treatment for cervical infection with Chlamydia trachomatis?
作者信息
Radcliffe K W, Rowen D, Mercey D E, Mumtaz G, Ridgway G L, Robinson A J, Bingham J S
机构信息
Department of Genitourinary Medicine, University College of and Middlesex Hospitals, London.
出版信息
Genitourin Med. 1990 Dec;66(6):444-6. doi: 10.1136/sti.66.6.444.
Tests of cure (TOC) were performed on specimens from 106 women following treatment for chlamydial infection of the cervix. 91 women attended for the first TOC with enzyme immunoassay (EIA) within one week of finishing antibiotics. Three were EIA positive, 88 were EIA negative. These three women were subsequently EIA and culture negative although they received no further antibiotics. Ninety women returned for the second TOC with EIA and culture between seven and 27 days after completing treatment. All the results were negative. Routine TOC is unnecessary following appropriate antichlamydial therapy. If TOC is indicated antigen-detection methods should not be used immediately after finishing antibiotics as misleading positive results may be obtained. EIA or culture at one week or later after treatment is reliable.
对106名宫颈衣原体感染女性治疗后的标本进行了治愈检测（TOC）。91名女性在完成抗生素治疗的一周内首次进行TOC检测，采用酶免疫测定法（EIA）。3名女性EIA检测呈阳性，88名女性EIA检测呈阴性。这3名女性随后EIA和培养检测均为阴性，尽管她们未接受进一步的抗生素治疗。90名女性在完成治疗后的7至27天返回进行第二次TOC检测，采用EIA和培养法。所有结果均为阴性。适当的抗衣原体治疗后无需进行常规TOC检测。如果需要进行TOC检测，在完成抗生素治疗后不应立即使用抗原检测方法，因为可能会获得误导性的阳性结果。治疗后一周或更晚进行EIA或培养检测是可靠的。
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