School of Sport and Exercise, Massey University, Wellington, New Zealand.
J Atheroscler Thromb. 2012;19(5):407-21. doi: 10.5551/jat.11395. Epub 2012 Mar 1.
The pathological complications of atherosclerosis, namely heart attacks and strokes, remain the leading cause of mortality in the Western world. Preceding atherosclerosis is endothelial dysfunction. There is therefore interest in the application of non-invasive clinical tools to assess endothelial function. The flow-mediated dilation (FMD) test is the standard tool used to assess endothelial function. Reduced FMD is an early marker of atherosclerosis and has been noted for its capacity to predict future cardiovascular disease events. This review discusses the measurement of endothelial function using ultrasound, with a focus on the FMD technique.
动脉粥样硬化的病理并发症，即心脏病发作和中风，仍然是西方世界的主要死亡原因。动脉粥样硬化之前是内皮功能障碍。因此，人们对应用非侵入性临床工具来评估内皮功能产生了兴趣。血流介导的扩张（FMD）测试是用于评估内皮功能的标准工具。FMD 降低是动脉粥样硬化的早期标志物，并因其能够预测未来心血管疾病事件而受到关注。本文综述了使用超声测量内皮功能，重点介绍了 FMD 技术。
