Vollet J J, Ericsson C D, Gibson G, Pickering L K, DuPont H L, Kohl S, Conklin R H
J Med Virol. 1979;4(2):81-7. doi: 10.1002/jmv.1890040202.
The role of human rotavirus in adult diarrhea was evaluated in 164 newly arrived US students attending summer school at an urban Mexican university. Rotavirus was identified in stool samples by electron microscopy. Rotavirus was found in 26 of 109 students with diarrhea (24%) and in 8 of 55 asymptomatic control students (15%). Although bacterial pathogens were recovered from virus positive students with diarrhea, viral shedding also occurred independently of other agents. Clinical disease in students excreting only rotavirus tended to be mild and was accompanied by a low density of viral shedding. Food consumption in the home and at public eating establishments was examined the week before illness. While the location of food consumption was found to be important in the acquisition of diarrhea, there was no apparent relationship of the site where meals were eaten and the acquisition of rotavirus by students newly arrived in Mexico. These data support our previous study in a US student population residing in a rural setting in Mexico and implicate rotavirus as a cause of diarrhea among students traveling to Mexico from the United States. The present study offers additional evidence that rotavirus infection in this population might be spread by a nonfood vehicle of transmission which differs from spread of enterotoxigenic E coli, Shigella, or Salmonella strains in the same population.
在一所墨西哥城市大学参加暑期课程的164名新入学美国学生中，评估了人轮状病毒在成人腹泻中的作用。通过电子显微镜在粪便样本中鉴定轮状病毒。在109名腹泻学生中的26名（24%）以及55名无症状对照学生中的8名（15%）粪便样本中发现了轮状病毒。虽然在腹泻的病毒阳性学生中也检测到了细菌病原体，但病毒排出也可独立于其他病原体发生。仅排出轮状病毒的学生临床疾病往往较轻，且病毒排出量较低。在发病前一周，调查了学生在家中和公共饮食场所的食物摄入情况。虽然发现食物摄入地点在腹泻的发生中很重要，但新到墨西哥的学生就餐地点与轮状病毒感染之间没有明显关联。这些数据支持了我们之前对居住在墨西哥农村地区的美国学生群体的研究，并表明轮状病毒是从美国前往墨西哥的学生腹泻的一个病因。本研究提供了更多证据，表明该人群中的轮状病毒感染可能通过一种非食物传播途径传播，这与同一人群中肠毒素性大肠杆菌、志贺氏菌或沙门氏菌菌株的传播方式不同。
