Bolivar R, Conklin R H, Vollet J J, Pickering L K, DuPont H L, Walters D L, Kohl S
J Infect Dis. 1978 Mar;137(3):324-7. doi: 10.1093/infdis/137.3.324.
The role of rotavirus in adult diarrhea was evaluated in 165 students attending a Mexican university. Students were divided into three groups: newly arrived summer students from the United Sttes, regular students from the United States, and Mexican and Venezuelan students. Ninety-one students with diarrhea and 74 corresponding, matched, asymptomatic control students were included in the study. The frequency of rotavirus in stools was determined by electron microscopy with use of the pseudoreplica technique. Twenty-five percent of those who were ill and 12% of the controls had rotavirus in their stools. A significantly (P less than 0.05) greater number of newly arrived United States summer students with diarrhea had rotavirus in their stool than did matched controls (26% vs. 3%). There was no significant difference in rate of recovery of bacterial pathogens from rotavirus-positive and rotavirus-negative stools (52% vs. 53%) from students with diarrhea. Although significantly more rotavirus was identified from ill American summer students than from controls, the role of rotavirus as a cause of diarrhea in these students could not be established in all cases since bacterial pathogens were also commonly found in stool.
在一所墨西哥大学就读的165名学生中，对轮状病毒在成人腹泻中的作用进行了评估。学生被分为三组：来自美国的新入学暑期学生、来自美国的普通学生以及墨西哥和委内瑞拉学生。该研究纳入了91名腹泻学生和74名相应的、匹配的无症状对照学生。通过使用假复制品技术的电子显微镜检查来确定粪便中轮状病毒的频率。患病学生中有25%的人粪便中含有轮状病毒，对照学生中有12%的人粪便中含有轮状病毒。腹泻的新入学美国暑期学生粪便中含有轮状病毒的人数显著（P小于0.05）多于匹配的对照学生（26%对3%）。腹泻学生的轮状病毒阳性粪便和轮状病毒阴性粪便中细菌病原体的检出率没有显著差异（52%对53%）。尽管从患病的美国暑期学生中检出的轮状病毒明显多于对照学生，但由于粪便中也普遍存在细菌病原体，因此在所有病例中都无法确定轮状病毒作为这些学生腹泻病因的作用。
