Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University), Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, PR China.
Org Lett. 2012 Jun 15;14(12):3116-9. doi: 10.1021/ol3012056. Epub 2012 Jun 5.
In the presence of catalytic amount of copper iodide, a remote amide-assisted intramolecular arylation followed by alkylation leads to a general and flexible synthetic method toward the synthesis of medicinally interesting hexahydropyrroloindole alkaloids.
在催化量碘化亚铜的存在下,远程酰胺辅助的分子内芳基化反应接着进行烷基化反应,从而得到一种通用且灵活的合成方法,用于合成具有药用价值的六氢吡咯并吲哚生物碱。