韩国正常眼压型青光眼患者的黄斑中心凹下脉络膜厚度测量。
Measurement of subfoveal choroidal thickness in normal-tension glaucoma in Korean patients.
机构信息
*Institute of Ophthalmology and Optometry †Department of Ophthalmology, Ewha Womans University School of Medicine, Seoul, Republic of Korea.
出版信息
J Glaucoma. 2014 Jan;23(1):46-9. doi: 10.1097/IJG.0b013e31825af772.
PURPOSE
To evaluate subfoveal choroidal thickness (CT) in eyes with normal-tension glaucoma (NTG) in patients who were visualized by enhanced depth imaging optical coherence tomography.
METHODS
In this observational, comparative case series, subfoveal CT was measured with enhanced depth imaging optical coherence tomography in 35 eyes of normal individuals and 32 eyes of patients with NTG. Subfoveal CT in each eye was analyzed by measuring the vertical distance from Bruch membrane to the innermost sclera layer.
RESULTS
The mean subfoveal CT in the normal individual group and the NTG patient group were 300.0±52.7 and 289.5±100.4 µm, respectively. There was no difference in subfoveal CT in the 2 groups (P=0.60). The mean subfoveal CT in all subjects was significantly correlated negatively with age only (P=0.03).
CONCLUSIONS
The subfoveal CT does not differ between the eyes of the normal individual group and the eyes in the NTG patient group, suggesting that CT may not play a role in the pathogenesis of NTG.
目的
利用增强深度成像光学相干断层扫描评估正常眼压性青光眼（NTG）患者的黄斑中心凹下脉络膜厚度（CT）。
方法
本研究为观察性、对照病例系列研究，使用增强深度成像光学相干断层扫描测量 35 只正常人眼和 32 只 NTG 患者眼的黄斑中心凹下 CT。通过测量从 Bruch 膜到最内层巩膜层的垂直距离来分析每只眼的黄斑中心凹下 CT。
结果
正常个体组和 NTG 患者组的平均黄斑中心凹下 CT 分别为 300.0±52.7 和 289.5±100.4 µm，两组间黄斑中心凹下 CT 无差异（P=0.60）。所有受试者的平均黄斑中心凹下 CT 仅与年龄呈显著负相关（P=0.03）。
结论
正常个体组和 NTG 患者组的黄斑中心凹下 CT 无差异，提示 CT 可能在 NTG 的发病机制中不起作用。
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